Leiomyosarcoma

third commonest lesion after liposarcoma and MFH. Large lesions show haemorrhage and necrosis. Poor prognosis generally. Commonest sarcoma to metastasise to the brain. Like their benign relatives lesions can be cutaneous, vascular or deep. Cutaneous have the best prognosis. Deep lesions occur in the fifth and sixth decade. Retroperitoneum commonest. Thigh is commonest peripheral location. Calcification may be seen.


Rhabdomyosarcoma

Extremity lesions are typically the alveolar type. Adolescents and young adults. Intramuscular prominent vessels may help to differentiate from other sarcomas but overall this is difficult.



Leiomyoma

can be superficial (arising in the skin), vascular or deep. The commonest soft tissue location is the uterus. Other locations are rare. When vessels are dominant the term vascular leiomyoma is used. Superficial leiomyoma arise from smooth muscle of the skin hair follicles they occur in young adults on extensor surfaces of the arms and legs. Lesions are usually small less than 2cm. The foot is a common location. Deep lesions are less common and may contain scattered calcification.


Rhabdomyoma

Extra cardiac incidence is rare. Affects middle aged men. Head and neck and 90%.. Third and fourth branchial arches especially larynx, pharynx and mouth.